Good heavens, YES! Over about 6 months I lost 10kg and, more importantly perhaps, 10cm off my waist. I wasn't obese (185cm tall, 84kg, 104cm waist) but was concerned about my waist line especially, as it is very unhealthy for men to have a waist over 94cm and women over 80cm.
I simply stopped eating or drinking stuff with fructose in it. This included cane sugar, honey, jam, Promite, cakes, chocolates, sweets etc. I had no withdrawal symptoms and no guilt about eating "party food' on appropriate occasions. My wife made no adjustments to her cooking practices which were pretty low in fat & sugar anyway. I just don't eat the stuff that has a lot of sugar in it. And I became an avid label reader when in the supermarket.
One bonus is that, after any withdrawal symptoms are gone, you don't have to worry about fat since it is the fructose which makes you fat, not fat. When your appetite-control system is working properly again you will only take in as much fat as you need - your body will tell your brain when you reach that point and you simply won't want any more. The same goes for food generally.
I've had all my best trousers reduced to fit comfortably and look and feel great for an 80 year old :-)
So . . GO FOR IT! Like stopping smoking, the more you achieve the better motivated you will be not to regress. If you need support, well here it is, in these forums!